The Cleanroom Construction Associates (CCA) staff has combined for over twenty different white papers and published articles in all avenues of cleanroom, design, construction, and operation. These articles are referenced below for review and use by our current or potential clients. Feel free to read through them and utilize any that you feel can assist your efforts. If you'd like more information, please contact the author directly.
whitepapers
March 14, 2015
Modular Cleanrooms – An Evolving Industry
Mark ForstControlled Environments magazineAn interview with Wayne McGee, owner of PortaFab Modular Building Systems, and Tim Loughran, owner of Cleanroom Construction Associates.
whitepapers
February 16, 2015
The Surprising Advantages of Modular Cleanrooms
Scott Mackler A2C2 magazine November 1998 Modular cleanrooms offer a number of advantages over those constructed using “stick-built” techniques. They can obviously be built quickly and readily configured, upgraded, expanded and even dismantled and moved.
Abstract The controversy over the use of air showers in the contamination control process has been ongoing for many years. The effectiveness of an Air Shower entry system relates directly to its proper design and use. In recent years tests […]
whitepapers
February 16, 2015
The Case for Design-Build Cleanroom Facilities Delivery
Scott Mackler Bio Processing Journal May/Jun 2003 In the past, most large construction projects used a system called design-bid-build. Now, pharmaceutical companies planning cleanrooms have begun using an improved system, design-build, which can save millions of dollars and cut months […]
whitepapers
February 16, 2015
Summary of USP* 797 – Pharmaceutical Compounding – Sterile Preparations
Source of base information: Pharmacopeial Form – Volume 29 (4) July – August 2003 Effective Date: January 1, 2004 FDA enforceable: yes Scope – “The content of this chapter applies to health care institutions, pharmacies, physicians practice facilities and other […]
whitepapers
February 16, 2015
Point of View: Facilities Cleanliness Requirements
When the solution is simple, God is answering. – Albert Einstein The relationship between facility cleanliness and product cleanliness, between design criteria and operational conditions is one that even today oftentimes remains a mystery. Particle fallout is the source of […]
whitepapers
February 16, 2015
Environmental Monitoring: Particle Counts are Easy
Scott Mackler February 2004 Manufacturing pharmaceutical and biotechnology products requires that the appropriate level of quality be designed and constructed into the facility — and systems — that support the production process. As a result of recent 483 observations and […]
whitepapers
February 16, 2015
Case Study: Cambrex Biosciences Process Development Lab Expansion
In the Summer of 2002, Cambrex Bio Science Baltimore, Inc. commissioned a 3rd Party engineering firm to develop a Basis of Design (BOD) document for the 30,000 ft2 expansion of their process development laboratories at their Baltimore facility. The expansion […]
whitepapers
February 16, 2015
Basis of Design for Life Science Cleanroom Facilities
Basis Of Design For Life Science Cleanroom Facilities by Scott E. Mackler April 1, 2010 The successful design and realization of a validatable life sciences cleanroom won’t happen by chance. Early and continuous coordination and communication among all parties involved […]
whitepapers
February 16, 2015
Basis of Design for Life Science Cleanroom Facilities – Part 2
Scott Mackler
A2C2
June 1998
It was Louis Sullivan, designer of so many of Chicago’s fames high-rise buildings, who wrote, in 1960, “Form ever follows function.”Years before, Winston Churchill had written, “We shape our buildings, and afterwards our buildings shape us.”
A2C2
June 1998
It was Louis Sullivan, designer of so many of Chicago’s fames high-rise buildings, who wrote, in 1960, “Form ever follows function.”Years before, Winston Churchill had written, “We shape our buildings, and afterwards our buildings shape us.”