The Cleanroom Construction Associates (CCA) staff has combined for over twenty different white papers and published articles in all avenues of cleanroom, design, construction, and operation. These articles are referenced below for review and use by our current or potential clients. Feel free to read through them and utilize any that you feel can assist your efforts. If you'd like more information, please contact the author directly.
Mark ForstControlled Environments magazineAn interview with Wayne McGee, owner of PortaFab Modular Building Systems, and Tim Loughran, owner of Cleanroom Construction Associates.
Scott Mackler A2C2 magazine November 1998 Modular cleanrooms offer a number of advantages over those constructed using “stick-built” techniques. They can obviously be built quickly and readily configured, upgraded, expanded and even dismantled and moved.
Abstract The controversy over the use of air showers in the contamination control process has been ongoing for many years. The effectiveness of an Air Shower entry system relates directly to its proper design and use. In recent years tests […]
Scott Mackler Bio Processing Journal May/Jun 2003 In the past, most large construction projects used a system called design-bid-build. Now, pharmaceutical companies planning cleanrooms have begun using an improved system, design-build, which can save millions of dollars and cut months […]
When the solution is simple, God is answering. – Albert Einstein The relationship between facility cleanliness and product cleanliness, between design criteria and operational conditions is one that even today oftentimes remains a mystery. Particle fallout is the source of […]
Scott Mackler February 2004 Manufacturing pharmaceutical and biotechnology products requires that the appropriate level of quality be designed and constructed into the facility — and systems — that support the production process. As a result of recent 483 observations and […]
Conor Murray, Contamination Control & Biosafety Expert Chairman, Irish Cleanroom Society, Chairman International Cleanroom Education Board Abstract This paper deals with biosafety change drivers, biosafety risk assessments, high containment biosafety design, secondary containment barrier design, commissioning & qualification as well […]
In the Summer of 2002, Cambrex Bio Science Baltimore, Inc. commissioned a 3rd Party engineering firm to develop a Basis of Design (BOD) document for the 30,000 ft2 expansion of their process development laboratories at their Baltimore facility. The expansion […]
Basis Of Design For Life Science Cleanroom Facilities by Scott E. Mackler April 1, 2010 The successful design and realization of a validatable life sciences cleanroom won’t happen by chance. Early and continuous coordination and communication among all parties involved […]